Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In vitro stimulation of ovarian tumour-associated lymphocytes with a peptide derived from HER2/neu induces cytotoxicity against autologous tumour.

Surgical oncology - 1 Feb 1995

Linehan D C, Peoples G E, Hess D T, Summerhayes I C, Parikh A S, Goedegebuure P S, Eberlein T J

Abstract excerpt

The proto-oncogene HER2/neu encodes for a 185 kDa transmembrane protein with extensive homology to the epidermal growth factor (EGF) receptor. We have previously shown a correlation between HER2/neu expression and the level of in vitro cytotoxicity of tumour-associated lymphocytes (TAL) versus autologous tumour. In addition, we have recently demonstrated that tumour-associated cytotoxic T-lymphocytes (CTL) from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Antibodies, Monoclonal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Base Sequence

Share to DNA, Complementary

Share to DNA, Neoplasm

Share to Molecular Sequence Data

Share to Phenotype

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 7780612
DOI: 10.1016/s0960-7404(10)80030-1

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In vitro stimulation of ovarian tumour-associated lymphocytes with a peptide derived from HER2/neu induces cytotoxicity against autologous tumour.PMID 7780612Read ↗

Identification of an immunodominant peptide of HER-2/neu protooncogene recognized by ovarian tumor-specific cytotoxic T lymphocyte lines.Semantic proximity Read ↗

Breast and ovarian cancer-specific cytotoxic T lymphocytes recognize the same HER2/neu-derived peptide.Semantic proximity Read ↗

HLA-B5-restricted auto-tumor-specific cytotoxic T cells generated in mixed lymphocyte-tumor-cell culture.Semantic proximity Read ↗

Tumor cytolysis by lymphocytes infiltrating ovarian malignant ascites.Semantic proximity Read ↗

Levels of Specific Peptide-HLA Class I Complex Predicts Tumor Cell Susceptibility to CTL KillingSemantic proximity Read ↗

Generation of cytotoxic effector cells against human melanoma.Semantic proximity Read ↗

In search of specific cytotoxic T lymphocytes infiltrating or accompanying human ovarian carcinoma.Semantic proximity Read ↗

Sustained outgrowth of autotumor-reactive T lymphocytes from human ovarian carcinomas in the presence of tumor necrosis factor alpha and interleukin 2.Semantic proximity Read ↗

Autologous tumour-specific cytotoxic T-cell clone established from tumour-infiltrating lymphocytes (TIL) of malignant ascites in the absence of recombinant interleukin 2(rIL2): activation by autologous tumour cell alone.Semantic proximity Read ↗

Fibronectin promotes the proliferation of cytotoxic T lymphocytes generated from cancer patients.Semantic proximity Read ↗

Induction of immunocellular resistance to IL-2-activated lymphocytes within ovarian carcinoma cells.Semantic proximity Read ↗

Differential regulation by interleukin-4 and interferon-gamma of an autologous melanoma-specific cytotoxic T-cell clone and the tumor-infiltrating lymphocytes from which it was established.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.