Article
Induction of immunocellular resistance to IL-2-activated lymphocytes within ovarian carcinoma cells.
Gynecologic oncology - 1 Jun 1995
Papadopoulos A J, Han X, Matossian-Rogers A, Raju K S
Abstract excerpt
The development of resistance within ovarian carcinoma cells to activated cytotoxic lymphocytes was the objective of this study. Primary ovarian carcinoma cells were obtained from the ascites of a patient. These cells were cocultured with IL-2-activated autologous tumor-associated lymphocytes (TALs) for 1 week. The resulting selected cells underwent a second coculture for 3 days with IL-2-activated autologous...
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