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Article

Fibronectin promotes the proliferation of cytotoxic T lymphocytes generated from cancer patients.

British journal of cancer - 1 Nov 1996

Mizobata S, Tanimura H, Yamaue H, Tani M, Tsunoda T, Iwahashi M, Noguchi K, Nishimoto N, Hotta T, Arii K

Abstract excerpt

We studied whether fibronectin (FN) enhances the activity of autologous tumour-reactive cytotoxic T lymphocytes (CTLs) generated from cancer patients. The proliferation of CTLs stimulated by immobilised anti-CD3 monoclonal antibody and interleukin 2 (IL-2) was enhanced three or four times by immo...

Topics

Adult
Aged
Aged, 80 and over
Cell Division
Cytokines
Female
Fibronectins
Humans
Lymphocyte Activation
Major Histocompatibility Complex
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasms

Phenotype

T-Lymphocytes, Cytotoxic

Source

Open in PubMed Open full text

Identifiers

PMID: 8932341
DOI: 10.1038/bjc.1996.595
PMCID: PMC2074855

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8932341-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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