Article
In search of specific cytotoxic T lymphocytes infiltrating or accompanying human ovarian carcinoma.
Cancer immunology, immunotherapy : CII - 1 Jan 1992
Apiranthitou-Drogari M, Paganin C, Bernasconi S, Losa G, Maneo A, Colombo N, Mantovani A, Allavena P
Abstract excerpt
Lymphocytes infiltrating human ovarian carcinoma obtained directly from the tumour mass (tumour-infiltrating lymphocytes, TIL) or from the carcinomatous ascites (tumour-associated lymphocytes, TAL) were expanded in vitro in long-term cultures with interleukin-2 and tested for their specific cytol...
Topics
- Cells, Cultured
- Clone Cells
- Cytotoxicity, Immunologic
- Female
- Humans
- Immunotherapy, Adoptive
- Interleukin-2
- Lymphocyte Culture Test, Mixed
- Lymphocytes, Tumor-Infiltrating
- Ovarian Neoplasms
- Phenotype
- T-Lymphocytes, Cytotoxic
- Time Factors
- Tumor Cells, Cultured