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Article

Augmentation of specific tumor killing activity by tumor-infiltrating lymphocytes (TIL) in the presence of TNF-SAM2.

Cancer biotherapy - 1 Jan 1995

Goto S, Suma Y, Noguchi K, Kera J, Sakai S, Soma G I, Takeuchi S

Abstract excerpt

The effect of TNF-SAM2 on cytotoxic activity of tumor-infiltrating lymphocytes (TIL) was investigated. TIL were prepared from 11 human cancer patients. They were propagated by double in vitro stimulation with anti-CD3 monoclonal antibody and interleukin-2, and cultured for 3 weeks. The cytotoxic activity of TIL was tested with standard 4h 51Cr-release assays in the presence or the absence of TNF-SAM2. In the...

Topics

Cytotoxicity, Immunologic
Humans
Lymphocytes, Tumor-Infiltrating
Phenotype
Surface Properties
Tumor Cells, Cultured
Tumor Necrosis Factor-alpha

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7780485
DOI: 10.1089/cbr.1995.10.37

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7780485-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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