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Article

A pilot study of intralymphatic interleukin-2. I. Cytotoxic and surface marker changes of peripheral blood lymphocytes.

Journal of biological response modifiers - 1 Feb 1990

Shau H, Isacescu V, Ibayashi Y, Tokuda Y, Golub S H, Fahey J L, Sarna G P

Abstract excerpt

Patients with metastatic solid tumors were treated with six escalating doses of weekly intralymphatically injected recombinant interleukin 2 (i.l. IL-2). Nine patients completed the treatment and were evaluated for immunologic features of their peripheral blood lymphocytes (PBLs). The patients' P...

Topics

Antigens, Differentiation
Cytotoxicity Tests, Immunologic
Humans
Injections, Intralymphatic
Interleukin-2
Killer Cells, Lymphokine-Activated
Killer Cells, Natural
Lymphocytes
Phenotype
Pilot Projects
Recombinant Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 2319261

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2319261-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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