Article
Application of DNA fingerprints for cell-line individualization.
American journal of human genetics - 1 Sept 1990
Gilbert D A, Reid Y A, Gail M H, Pee D, White C, Hay R J, O'Brien S J
Abstract excerpt
DNA fingerprints of 46 human cell lines were derived using minisatellite probes for hypervariable genetic loci. The incidence of 121 HaeIII DNA fragments among 33 cell lines derived from unrelated individuals was used to estimate allelic and genotypic frequencies for each fragment and for composite individual DNA fingerprints. We present a quantitative estimate of the extent of genetic difference between...
Topics
- Alleles
- Blotting, Southern
- Cell Line
- DNA
- DNA Probes
- DNA, Satellite
- Genotype
- HeLa Cells
- Humans
- Models, Genetic
- Nucleotide Mapping
- Polymorphism, Restriction Fragment Length