Article
Gene expression in a temperature-sensitive mutant of the cell cycle.
SAAS bulletin, biochemistry and biotechnology - 1 Jan 1994
Hirschhorn R R
Abstract excerpt
The proliferative response of mammalian fibroblasts to growth stimulation requires gene expression, including an increase in RNA synthesis. Vimentin, a class III intermediate filament, has been shown to be encoded by a growth-regulated gene whose mRNA levels increase after serum stimulation of quiescent hamster fibroblasts. This induction is a consequence of increased vimentin-specific transcriptional activity...
Topics
- Animals
- Blotting, Northern
- Cell Cycle
- Cell Line
- Cell Nucleus
- Cricetinae
- Cytoplasm
- Fibroblasts
- Gene Expression
- Kidney
- Mesocricetus
- Mutation