Misdirected vimentin messenger RNA alters cell morphology and motility.

doi:10.1242/jcs.113.13.2433

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Article

Misdirected vimentin messenger RNA alters cell morphology and motility.

Journal of cell science - 1 Jul 2000

Morris E J, Evason K, Wiand C, L'Ecuyer T J, Fulton A B

Abstract excerpt

Localized messenger RNAs were first observed as embryonic determinants that altered development when mislocalized. In recent years localized mRNAs have been found for several cytoskeletal proteins, including actin, vimentin and several microtubule associated proteins. We sought to determine whether redirecting mRNA for a cytoskeletal protein to an inappropriate address would alter cellular phenotypes. To do so we...

Topics

Animals
Cell Movement
Cell Size
Cells, Cultured
Chick Embryo
Cytoskeleton
Fibroblasts
Phenotype
RNA, Messenger
Vimentin

Source

Open in PubMed

Identifiers

PMID: 10852822
DOI: 10.1242/jcs.113.13.2433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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