Article
Effect of mutations of murine lens alphaB crystallin on transfected neural cell viability and cellular translocation in response to stress.
FEBS letters - 30 Oct 1998
Wiesmann K E, Coop A, Goode D, Hepburne-Scott H W, Crabbe M J
Abstract excerpt
We examined the influence of over-expressed native and mutant murine lens alphaB crystallin on the response of a murine neural cell line to heat and ionic strength shock. Native and mutant (F27R and KK174/175LL) murine alphaB crystallin amplicons were subcloned into a Lac-Switch IPTG-inducible RS...
Topics
- Amino Acid Sequence
- Animals
- Cell Movement
- Cell Survival
- Crystallins
- Heat-Shock Response
- Humans
- Mice
- Microscopy, Confocal
- Molecular Sequence Data
- Mutation
- Neuroblastoma
- Neurons
- Osmolar Concentration
- Phenotype
- Sequence Alignment
- Transfection
- Tumor Cells, Cultured
