Article
Apolipoprotein E and Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America - 23 May 1995
Strittmatter W J, Roses A D
Abstract excerpt
Inheritance of specific apolipoprotein E (apoE) alleles determines, in large part, the risk and mean age of onset of late-onset familial and sporadic Alzheimer disease. The mechanism by which the apoE isoforms differentially contribute to disease expression is, however, unknown. Isoform-specific...
Topics
- Age Factors
- Alleles
- Alzheimer Disease
- Amyloid beta-Peptides
- Apolipoproteins E
- Brain
- Humans
- Neurites
- Risk Factors
- tau Proteins