Article
Morphological, biochemical, and genetic support for an apolipoprotein E effect on microtubular metabolism.
Annals of the New York Academy of Sciences - 17 Jan 1996
Roses A D, Einstein G, Gilbert J, Goedert M, Han S H, Huang D, Hulette C, Masliah E, Pericak-Vance M A, Saunders A M, Schmechel D E, Strittmatter W J, Weisgraber K H, Xi P T
Abstract excerpt
There are two distinct viewpoints on the association of the inheritance of apolipoprotein E (APOE) alleles and the age of onset distribution of Alzheimer's disease (AD): genetic and phenotypic expression. There have been multiple corroborations of the APOE-epsilon 4 association with Alzheimer's disease in populations around the world in clinic based studies as well as emerging epidemiological studies. The genetic...
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