Article
Transcriptional and posttranscriptional regulations of the HLA-G gene.
Journal of immunology research - 1 Jan 2014
Castelli Erick C, Veiga-Castelli Luciana C, Yaghi Layale, Moreau Philippe, Donadi Eduardo A
Abstract excerpt
HLA-G has a relevant role in immune response regulation. The overall structure of the HLA-G coding region has been maintained during the evolution process, in which most of its variable sites are synonymous mutations or coincide with introns, preserving major functional HLA-G properties. The HLA-G promoter region is different from the classical class I promoters, mainly because (i) it lacks regulatory responsive...
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