Article
Promoter sequences confirm the three different evolutionary lineages described for HLA-G.
Human immunology - 1 Mar 2013
Martinez-Laso J, Herraiz M A, Peñaloza J, Barbolla M L, Jurado M L, Macedo J, Vidart J, Cervera I
Abstract excerpt
HLA-G alleles follow a different pattern of polymorphism generation that those of the HLA classical I alleles. However, this polymorphism maintenance could have an evolutionary specific pathways based on non coding regions as introns, 14 bp deletion/insertion (exon 8) or promoter regions. For this reason, a systematic sequencing study of HLA-G promoter region was done in 36 individuals with a total of 15...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
