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Article

Evidence of balancing selection at the HLA-G promoter region

19 Oct 2005

Abstract excerpt

HLA-G is a class Ib HLA gene with unique tissue expression pattern and immunomodulatory properties. Polymorphisms in the HLA-G promoter region have been associated with miscarriage and asthma, whereas expression levels have been associated with a wide range of pathologic conditions as well as survival of embryos after in vitro fertilization and of organs after transplantation. Here, we characterize the sequence...

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Identifiers

PMID: 16236759
DOI: 10.1093/hmg/ddi389

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Source receipt: pubmed, retrieved 7 Sept 2026.

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