Article
Polymorphism in the promoter region of the gene encoding human allograft inflammatory factor-1.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Aug 2001
Turner D M, Pravica V, Sinnott P J, Hutchinson I V
Abstract excerpt
We have identified a new single nucleotide polymorphism within the promoter region of the human allograft inflammatory factor (AIF-1) gene. The polymorphism, defined by Genbank accession number AF097515, was characterized as a C/T single base pair substitution at position -932. The T allele is associated with both HLA-DR2 and HLA-B7. Also, this allele creates the consensus binding site for the E-box that has high...
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