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Article

Genetic variation of the IL-28B promoter affecting gene expression.

PloS one - 1 Jan 2011

Sugiyama Masaya, Tanaka Yasuhito, Wakita Takaji, Nakanishi Makoto, Mizokami Masashi

Abstract excerpt

The current standard of care for the treatment of chronic hepatitis C is pegylated interferon-α (PEG-IFNα) and ribavirin (RBV). The treatment achieves a sustained viral clearance in only approximately 50% of patients. Recent whole genome association studies revealed that single nucleotide polymorphisms (SNPs) around IL-28B have been associated with response to the standard therapy and could predict treatment...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22046316
DOI: 10.1371/journal.pone.0026620
PMCID: PMC3201970

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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