Article
Identification of a regulatory function for an orphan receptor in muscle: COUP-TF II affects the expression of the myoD gene family during myogenesis.
Nucleic acids research - 25 Apr 1995
Muscat G E, Rea S, Downes M
Abstract excerpt
COUP-TF II is an 'orphan steroid receptor' that binds a wide variety of AGGTCA repeats and represses thyroid hormone (T3) and retinoid dependent trans-activation; however, very little is known of its functional and/or developmental role during mammalian cell differentiation. T3 and retinoids have...
Topics
- Actins
- Animals
- Base Sequence
- COUP Transcription Factors
- Cell Differentiation
- Cell Line
- DNA
- DNA-Binding Proteins
- Escherichia coli
- Gene Expression Regulation, Developmental
- Humans
- Mice
- Molecular Sequence Data
- Muscle, Skeletal
- Mutation
- MyoD Protein
- Myogenin
- Myosins