Article
Two adjacent MyoD1-binding sites regulate expression of the acetylcholine receptor alpha-subunit gene.
Nature - 24 May 1990
Piette J, Bessereau J L, Huchet M, Changeux J P
Abstract excerpt
Several genes encoding putative myogenic regulatory factors have been isolated on the basis of their ability to convert nonmuscle cells into myoblasts. Four of these genes code for nuclear proteins that belong to a larger family characterized by a conserved helix-loop-helix motif required for DNA-binding and dimerization. At least one protein, MyoD1, can function as a transcription factor and activate...
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