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Article

Characterization of a novel thyroid hormone receptor alpha variant involved in the regulation of myoblast differentiation.

Molecular endocrinology (Baltimore, Md.) - 1 Apr 2006

Casas François, Busson Muriel, Grandemange Stéphanie, Seyer Pascal, Carazo Angel, Pessemesse Laurence, Wrutniak-Cabello Chantal, Cabello Gérard

Abstract excerpt

The regulation of gene expression by thyroid hormone (T3) involves binding of the hormone to nuclear receptors [thyroid hormone receptor (TR)] acting as T3-dependent transcription factors encoded by TRalpha (NR1A1) and TRbeta (NR1A2) genes. Several TRalpha variants have already been characterized, but only some of them display T3 binding activity. In this study, we have identified another transcript,...

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Identifiers

PMID: 16322094
DOI: 10.1210/me.2005-0074

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