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Article

The nuclear orphan receptor COUP-TFII is required for limb and skeletal muscle development.

Molecular and cellular biology - 1 Dec 2004

Lee Christopher T, Li Luoping, Takamoto Norio, Martin James F, Demayo Francesco J, Tsai Ming-Jer, Tsai Sophia Y

Abstract excerpt

The nuclear orphan receptor COUP-TFII is widely expressed in multiple tissues and organs throughout embryonic development, suggesting that COUP-TFII is involved in multiple aspects of embryogenesis. Because of the early embryonic lethality of COUP-TFII knockout mice, the role of COUP-TFII during limb development has not been determined. COUP-TFII is expressed in lateral plate mesoderm of the early embryo prior to...

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Identifiers

PMID: 15572686
DOI: 10.1128/MCB.24.24.10835-10843.2004
PMCID: PMC533959

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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