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Article

Resistance of hippocampal synaptic transmission to hypoxia in carbonic anhydrase II-deficient mice.

Brain research - 13 Feb 1995

Velísek L, Moshé S L, Stanton P K

Abstract excerpt

Mutant Car2n/Car2n mice deficient in carbonic anhydrase II (CA II; a major brain CA isozyme) suffer from systemic acidosis and are more resistant to experimental seizures than their normal littermates (+/+ or +/Car2n). The N-methyl-D-aspartate (NMDA) subtype of glutamate receptor has been shown to contribute to long-term potentiation (LTP) of synaptic transmission, hypoxic/ischemic neuronal injury and to be...

Topics

Animals
Carbonic Anhydrases
Hippocampus
Hypoxia, Brain
Long-Term Potentiation
Male
Mice
Mutation
Synapses
Synaptic Transmission

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7743211
DOI: 10.1016/0006-8993(94)01336-g

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7743211-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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