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Article

Breathing without CO(2) chemosensitivity in conditional Phox2b mutants.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 7 Sept 2011

Ramanantsoa Nelina, Hirsch Marie-Rose, Thoby-Brisson Muriel, Dubreuil Véronique, Bouvier Julien, Ruffault Pierre-Louis, Matrot Boris, Fortin Gilles, Brunet Jean-François, Gallego Jorge, Goridis Christo

Abstract excerpt

Breathing is a spontaneous, rhythmic motor behavior critical for maintaining O(2), CO(2), and pH homeostasis. In mammals, it is generated by a neuronal network in the lower brainstem, the respiratory rhythm generator (Feldman et al., 2003). A century-old tenet in respiratory physiology posits that the respiratory chemoreflex, the stimulation of breathing by an increase in partial pressure of CO(2) in the blood,...

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Identifiers

PMID: 21900566
DOI: 10.1523/JNEUROSCI.1721-11.2011
PMCID: PMC6623392

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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