Article
Carbonic anhydrase XIV deficiency produces a functional defect in the retinal light response.
Proceedings of the National Academy of Sciences of the United States of America - 15 May 2007
Ogilvie Judith Mosinger, Ohlemiller Kevin K, Shah Gul N, Ulmasov Barbara, Becker Timothy A, Waheed Abdul, Hennig Anne K, Lukasiewicz Peter D, Sly William S
Abstract excerpt
Members of the carbonic anhydrase (CA) family play an important role in the regulation of pH, CO(2), ion, and water transport. CA IV and CA XIV are membrane-bound isozymes expressed in the eye. CA IV immunostaining is limited to the choriocapillaris overlying the retina, whereas CA XIV is expressed within the retina in Müller glial cells and retinal pigment epithelium. Here, we have characterized the...
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