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Article

Central chemoreception: lessons from mouse and human genetics.

Respiratory physiology & neurobiology - 31 Oct 2010

Goridis Christo, Brunet Jean-François

Abstract excerpt

The response to increased P(CO(2)) in the brain is an essential drive to breathe and required for CO(2) and pH homeostasis in the blood, but where and how CO(2) is sensed are still contentious issues. Here, we review evidence from mouse and human genetics that argue for the crucial role in CO(2) chemosensitivity of a limited set of central neurons that express the Phox2b transcription factor and are disabled by...

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Identifiers

PMID: 20307691
DOI: 10.1016/j.resp.2010.03.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Central chemoreception: lessons from mouse and human genetics.PMID 20307691Read ↗

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