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Article

Enhanced sensitivity of hippocampal pyramidal neurons from mdx mice to hypoxia-induced loss of synaptic transmission.

15 Mar 1992

Abstract excerpt

The gene at the Duchenne/Becker muscular dystrophy locus encodes dystrophin, a member of a protein superfamily that links the actin cytoskeleton to transmembrane plasmalemmal proteins. In mature skeletal myocytes, the absence of dystrophin is associated with decreased membrane stability, altered kinetics of several calcium channels, and increased intracellular calcium concentration. In the central nervous system,...

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Identifiers

PMID: 1549609
DOI: 10.1073/pnas.89.6.2461

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Source receipt: pubmed, retrieved 7 Sept 2026.

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