Article
Involvement of p53 expression in cAMP-mediated apoptosis in immortalized granulosa cells.
Experimental cell research - 1 May 1995
Keren-Tal I, Suh B S, Dantes A, Lindner S, Oren M, Amsterdam A
Abstract excerpt
In the accompanying paper we described the induction of apoptosis by extended cyclic AMP (cAMP)-mediated signals in primary granulosa cells and the reduction in this process in transformed cells expressing SV40 T antigen. In the present work, we examined the effect of overexpression of either wild-type or mutant p53 on cAMP-mediated apoptosis in steroidogenic granulosa cell lines transfected with SV40 DNA...
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