Article
Contribution of apoptosis to the phenotypic changes of adrenocortical cells in primary culture.
Molecular and cellular endocrinology - 28 Apr 1995
Negoescu A, Labat-Moleur F, Defaye G, Mezin P, Drouet C, Brambilla E, Chambaz E M, Feige J J
Abstract excerpt
The aim of this study was to evaluate the occurrence and physiological consequences of apoptosis in primary cultures of bovine adrenocortical cells (of fasciculata-reticularis origin). Under ACTH-free culture conditions, we observed apoptotic cells in the cell layer and the accumulation of apopto...
Topics
- Adrenal Cortex
- Adrenocorticotropic Hormone
- Animals
- Apoptosis
- Cattle
- Cell Count
- Cell Differentiation
- Cells, Cultured
- Chromatin
- Cytochrome P-450 CYP11B2
- Cytochrome P-450 Enzyme System
- DNA
- Microscopy, Electron
- Phenotype
- Steroid 11-beta-Hydroxylase