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Article

8-Cl-cAMP affects glioma cell-cycle kinetics and selectively induces apoptosis.

Cancer investigation - 1 Jan 2002

Grbovic Olivera, Jovic Viktor, Ruzdijic Sabera, Pejanovic Vjera, Rakic Ljubisav, Kanazir Selma

Abstract excerpt

8-Chloro-cyclic-adenosine-3',5'-monophosphate (8-Cl-cAMP), a site-selective synthetic cyclic adenosine 3',5'-monophosphate (cAMP) analog exhibits growth inhibition in a broad spectrum of human cancer lines. However, detailed studies on the effects exerted by cAMP analogs on cell-cycle kinetics have been lacking. We have examined and compared the effect of 8-Cl-cAMP on cell-cycle kinetics in two human glioma cell...

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Identifiers

PMID: 12449730
DOI: 10.1081/cnv-120005913

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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