Article
8-Cl-cAMP affects glioma cell-cycle kinetics and selectively induces apoptosis.
Cancer investigation - 1 Jan 2002
Grbovic Olivera, Jovic Viktor, Ruzdijic Sabera, Pejanovic Vjera, Rakic Ljubisav, Kanazir Selma
Abstract excerpt
8-Chloro-cyclic-adenosine-3',5'-monophosphate (8-Cl-cAMP), a site-selective synthetic cyclic adenosine 3',5'-monophosphate (cAMP) analog exhibits growth inhibition in a broad spectrum of human cancer lines. However, detailed studies on the effects exerted by cAMP analogs on cell-cycle kinetics ha...
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