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Article

Single-strand conformation polymorphism analysis by perpendicular temperature-gradient gel electrophoresis.

Electrophoresis - 1 Jan 1995

Sugano K, Fukayama N, Ohkura H, Shimosato Y, Yamada Y, Inoue T, Sekiya T, Hayashi K

Abstract excerpt

Using a newly developed temperature-gradient gel electrophoresis apparatus, mutations in the K-ras oncogene and p53 tumor suppressor gene were analyzed for single-strand conformation polymorphism (SSCP). The mobilities of single-stranded DNAs, carrying various mutations, change--depending on the gel temperature during electrophoresis. Therefore, temperature-gradient single-strand conformation polymorphism...

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PMID: 7737095
DOI: 10.1002/elps.1150160103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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