Article
Multitemperature single-strand conformation polymorphism.
Electrophoresis - 1 Oct 2001
Kaczanowski R, Trzeciak L, Kucharczyk K
Abstract excerpt
Changes of gel temperature during single-strand conformation polymorphism (SSCP) electrophoresis increase the sensitivity of mutation detection in polymerase chain reaction (PCR) products and significantly reduce the overall time and costs of analysis. Based on these findings, a new method for single nucleotide polymorphism (SNP) and point mutation detection--multitemperature single-strand conformation...
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