Analysis of single-strand DNA conformation polymorphism by capillary electrophoresis.

doi:10.1016/0021-9673(95)00430-0

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Article

Analysis of single-strand DNA conformation polymorphism by capillary electrophoresis.

Journal of chromatography. A - 26 Jan 1996

Arakawa H, Nakashiro S, Maeda M, Tsuji A

Abstract excerpt

Analysis of single-strand conformation polymorphism (SSCP) by capillary electrophoresis (CE) was developed. The conformational change of single-strand DNA is caused by a mutation in a DNA fragment. The change is detected as mobility shift in CE. The effects of acrylamide gel concentration, runnin...

Topics

Base Sequence
DNA, Bacterial
Electrophoresis, Capillary
Escherichia coli
Genes, Bacterial
Genes, ras
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Temperature

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