[Characterization of the mechanism of cross-resistance to vinca alkaloids and taxoids in the human J82 bladder tumor cell line].

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Article

[Characterization of the mechanism of cross-resistance to vinca alkaloids and taxoids in the human J82 bladder tumor cell line].

Bulletin du cancer - 1 Oct 1994

Debal V, Allam N, Morjani H, Millot J M, Gourdier B, Breillout F, Manfait M

Abstract excerpt

A phenotype of resistance to the new vinca alkaloid Navelbine was induced in the J82 human bladder carcinoma cells. The resistance factor of the resistant cell line (J82-NVB) to Navelbine was 17. The resistance phenotype of these cells is not a multidrug-resistance (MDR) phenotype. J82-NVB cells...

Topics

Antineoplastic Agents
Carcinoma
Colchicine
Doxorubicin
Drug Resistance, Multiple
Gene Expression Regulation, Neoplastic
Humans
Paclitaxel
Phenotype
Podophyllotoxin
Tumor Cells, Cultured
Urinary Bladder Neoplasms
Vinblastine
Vinorelbine

Source

Open in PubMed

Identifiers

PMID: 7734773

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7734773-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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