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Article

Altered subcellular location of an activated and tumour-associated epidermal growth factor receptor.

Oncogene - 6 Apr 1995

Ekstrand A J, Liu L, He J, Hamid M L, Longo N, Collins V P, James C D

Abstract excerpt

The epidermal growth factor (EGF) receptor is a membrane bound tyrosine kinase whose activity is initiated by ligand binding. The malignant brain tumour glioblastoma frequently shows amplification and rearrangements of the EGF receptor gene that are associated with the synthesis of a constitutively activated tyrosine kinase, lacking amino acids 6-273 near the protein's N-terminus. When expressed in Chinese...

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Source

Identifiers

PMID: 7731699

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Altered subcellular location of an activated and tumour-associated epidermal growth factor receptor.PMID 7731699Read ↗

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