Increased frequencies of HPRT mutant T lymphocytes in patients with Guillain-Barré syndrome and chronic inflammatory demyelinating polyneuropathy: further evidence for a role of T cells in the etiopathogenesis of peripheral demyelinating diseases.

doi:10.1016/0165-5728(94)00185-q

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Article

Increased frequencies of HPRT mutant T lymphocytes in patients with Guillain-Barré syndrome and chronic inflammatory demyelinating polyneuropathy: further evidence for a role of T cells in the etiopathogenesis of peripheral demyelinating diseases.

Journal of neuroimmunology - 1 Apr 1995

Van den Berg L H, Mollee I, Wokke J H, Logtenberg T

Abstract excerpt

We have used the HPRT mutant clonal assay to determine the frequency of mutant T lymphocytes (FMC), as a measure of recent T cell stimulation, in the blood of patients with Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyneuropathy (CIDP). We found that, compared to healt...

Topics

Adolescent
Adult
Aged
Clone Cells
Demyelinating Diseases
Humans
Hypoxanthine Phosphoribosyltransferase
Immunophenotyping
Middle Aged
Mutation
Polyradiculoneuropathy
Reference Values
T-Lymphocytes

Source

Open in PubMed

Identifiers

PMID: 7730448
DOI: 10.1016/0165-5728(94)00185-q

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7730448-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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