Assessment of clinical parameters associated with increased frequency of mutant T cells in patients with systemic lupus erythematosus.

doi:10.1002/art.1780370217

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Article

Assessment of clinical parameters associated with increased frequency of mutant T cells in patients with systemic lupus erythematosus.

Arthritis and rheumatism - 1 Feb 1994

Dawisha S M, Gmelig-Meyling F, Steinberg A D

Abstract excerpt

OBJECTIVE: To determine the clinical features that contribute to an increased frequency of mutant T cells (FMC) in patients with systemic lupus erythematosus (SLE). METHODS: During in vivo T cell division, there are errors in replication which give rise to mutations throughout the genome. An esti...

Topics

Adult
Azathioprine
Cell Division
Clone Cells
Cyclophosphamide
Female
Humans
Lupus Erythematosus, Systemic
Male
Middle Aged
Mutation
Regression Analysis
T-Lymphocytes
Thioguanine
Time Factors

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