Article
TBP mutants defective in activated transcription in vivo.
The EMBO journal - 3 Apr 1995
Arndt K M, Ricupero-Hovasse S, Winston F
Abstract excerpt
The TATA box binding protein (TBP) plays a central and essential role in transcription initiation. At TATA box-containing genes transcribed by RNA polymerase II, TBP binds to the promoter and initiates the assembly of a multiprotein preinitiation complex. Several studies have suggested that bindi...
Topics
- Amino Acid Sequence
- Base Sequence
- Blotting, Northern
- DNA Primers
- DNA-Binding Proteins
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Genotype
- Molecular Sequence Data
- Point Mutation
- Polymerase Chain Reaction
- Promoter Regions, Genetic
- RNA, Fungal
- Saccharomyces cerevisiae
- TATA-Box Binding Protein
- Transcription Factors
- Transcription, Genetic
- beta-Galactosidase