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Article

Transcription activation in cells lacking TAFIIS.

Nature - 12 Sept 1996

Walker S S, Reese J C, Apone L M, Green M R

Abstract excerpt

The general transcription factor TFIID is composed of the TATA-box-binding protein (TBP) and a set of TBP-associated factors (TAFIIs). In vitro, TAFIIs are required for activated transcription, and have been proposed to be obligatory targets of transcriptional activator proteins (activators)2. The function of TAFIIs has not been investigated systematically in vivo. A Saccharomyces cerevisiae TAFII complex (yTAFII...

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Source

Identifiers

PMID: 8774886
DOI: 10.1038/383185a0

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcription activation in cells lacking TAFIIS.PMID 8774886Read ↗

TBP-associated factors are not generally required for transcriptional activation in yeast.Semantic proximity Read ↗

Yeast TAF(II)90 is required for cell-cycle progression through G2/M but not for general transcription activation.Semantic proximity Read ↗

Distinct classes of yeast promoters revealed by differential TAF recruitment.Semantic proximity Read ↗

Broad, but not universal, transcriptional requirement for yTAFII17, a histone H3-like TAFII present in TFIID and SAGA.Semantic proximity Read ↗

Region of yeast TAF 130 required for TFIID to associate with promoters.Semantic proximity Read ↗

Systematic analysis of essential yeast TAFs in genome-wide transcription and preinitiation complex assembly.Semantic proximity Read ↗

Kin28 depletion increases association of TFIID subunits Taf1 and Taf4 with promoters in Saccharomyces cerevisiae.Semantic proximity Read ↗

TFIIA has activator-dependent and core promoter functions in vivo.Semantic proximity Read ↗

Analysis of TFIIA function In vivo: evidence for a role in TATA-binding protein recruitment and gene-specific activation.Semantic proximity Read ↗

Genome-wide analysis of transcriptional dependence and probable target sites for Abf1 and Rap1 in Saccharomyces cerevisiae.Semantic proximity Read ↗

Analysis of structure-function relationships of yeast TATA box binding factor TFIID.Semantic proximity Read ↗

The YEATS domain of Taf14 in Saccharomyces cerevisiae has a negative impact on cell growth.Semantic proximity Read ↗

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