Article
What association analysis can and cannot tell us about the genetics of complex disease.
American journal of medical genetics - 15 Dec 1994
Hodge S E
Abstract excerpt
Human genetics researchers have been intrigued for many years by weak-to-moderate associations between markers and diseases. However, in most cases of association, the cause of this phenomenon is still unknown. Recently, interest has grown in pursuing association studies for complex psychiatric diseases, either instead of or in addition to linkage studies. However, it is one thing to detect association; the next...
Topics
- Alcoholism
- Bipolar Disorder
- Female
- Genetic Predisposition to Disease
- Genetics, Medical
- Humans
- Male
- Mental Disorders
- Models, Genetic
- Pedigree
- Risk Factors