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Article

Genome-Wide Causation Studies of Complex Diseases.

Journal of computational biology : a journal of computational molecular cell biology - 1 Aug 2022

Jiao Rong, Chen Xiangning, Boerwinkle Eric, Xiong Momiao

Abstract excerpt

Despite significant progress in dissecting the genetic architecture of complex diseases by genome-wide association studies (GWAS), the signals identified by association analysis may not have specific pathological relevance to diseases so that a large fraction of disease-causing genetic variants is still hidden. Association is used to measure dependence between two variables or two sets of variables. GWAS test...

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PMID: 35451855
DOI: 10.1089/cmb.2021.0676

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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