Article
How to model a complex trait. 1. General considerations and suggestions.
Human heredity - 1 Jan 2003
Strauch Konstantin, Fimmers Rolf, Baur Max P, Wienker Thomas F
Abstract excerpt
Usually, when complex traits are at issue, not only are the loci of the responsible genes a priori unknown; the same also holds for the mode of inheritance of the trait, and sometimes even for the phenotype definition. The term mode of inheritance relates to both the genetic mechanism, i.e., the number of loci implicated in the etiology of the disease, and the genotype-phenotype relation, which describes the...
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