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Article

A two-stage variable-stringency semiparametric method for mapping quantitative-trait loci with the use of genomewide-scan data on sib pairs.

American journal of human genetics - 1 Mar 2000

Ghosh S, Majumder P P

Abstract excerpt

Genomewide scans for mapping loci have proved to be extremely powerful and popular. We present a semiparametric method of mapping a quantitative-trait locus (QTL) or QTLs with the use of sib-pair data generated from a two-stage genomic scan. In a two-stage genomic scan, either the entire genome or a large portion of the genome is saturated with low-density markers at the first stage. At the second stage, the...

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Identifiers

PMID: 10712217
DOI: 10.1086/302815
PMCID: PMC1288141

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