Increased ubiquitin expression suppresses the cell cycle defect associated with the yeast ubiquitin conjugating enzyme, CDC34 (UBC3). Evidence for a noncovalent interaction between CDC34 and ubiquitin.

Abstract excerpt

The yeast ubiquitin (Ub) conjugating enzyme CDC34 plays a crucial role in the progression of the cell cycle from the G1 to S phase. In an effort to identify proteins that interact with CDC34 we undertook a genetic screen to isolate genes whose increased expression suppressed the cell cycle defect...

Topics

• Alleles
• Anaphase-Promoting Complex-Cyclosome
• Cell Cycle
• Fungal Proteins
• Ligases
• Mutation
• Ubiquitin-Protein Ligase Complexes
• Ubiquitin-Protein Ligases
• Ubiquitins