Article
Microsatellite instability in inherited and sporadic neoplasms.
Current opinion in oncology - 1 Jan 1995
Eshleman J R, Markowitz S D
Abstract excerpt
Microsatellite instability (the replication error phenotype) is a new molecular assay that identifies a substantial fraction of human cancers. The microsatellite instability in these cancers arises from alterations in the tumors of the number of mono-, di-, and trinucleotide repeats that compose the microsatellites. Microsatellite instability is typical of colon and endometrial tumors arising in members of Lynch...
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