Article
Microsatellite instability in inherited and sporadic neoplasms.
Current opinion in oncology - 1 Jan 1995
Eshleman J R, Markowitz S D
Abstract excerpt
Microsatellite instability (the replication error phenotype) is a new molecular assay that identifies a substantial fraction of human cancers. The microsatellite instability in these cancers arises from alterations in the tumors of the number of mono-, di-, and trinucleotide repeats that compose...
Topics
- Colorectal Neoplasms, Hereditary Nonpolyposis
- DNA Damage
- DNA Repair
- DNA Replication
- DNA, Satellite
- Humans
- Neoplasms
- Phenotype