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Article

Microsatellite instability in primary and metastatic colorectal cancers.

International journal of cancer - 22 Jun 1995

Ishimaru G, Adachi J, Shiseki M, Yamaguchi N, Muto T, Yokota J

Abstract excerpt

Microsatellite instability characterizes a sub-set of sporadic colorectal cancers (CRCs) as well as CRCs from patients with hereditary non-polyposis colorectal cancer (HNPCC). In order to clarify when the cells acquire a replication-error phenotype (RER) during colorectal-tumor progression, we examined the incidence of RER in 80 primary tumors and 36 liver metastases at 8 microsatellite loci; 1 mono-, 5 di-, 1...

Topics

Adult
Aged
Base Sequence
Colorectal Neoplasms
DNA Replication
DNA, Satellite
Female
Humans
Liver Neoplasms
Male
Middle Aged
Molecular Sequence Data

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Identifiers

PMID: 7622302
DOI: 10.1002/ijc.2910640302

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7622302-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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