Microsatellite instability in human solid tumors.

doi:10.1016/S1357-4310(96)10055-1

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Article

Microsatellite instability in human solid tumors.

Molecular medicine today - 1 Feb 1997

Lothe R A

Abstract excerpt

A genome-wide instability has been found in almost all analyzed malignant tumors from patients with hereditary non-polyposis colorectal cancer (HNPCC), and in a subgroup of sporadic (non-inherited) cancers of the same type. This mutator phenotype was initially seen as novel alleles at microsatell...

Topics

Adaptor Proteins, Signal Transducing
Adenosine Triphosphatases
Bacteria
Carrier Proteins
Colorectal Neoplasms, Hereditary Nonpolyposis
DNA Repair
DNA Repair Enzymes
DNA-Binding Proteins
Fungal Proteins
Humans
Microsatellite Repeats
Mismatch Repair Endonuclease PMS2
MutL Protein Homolog 1
MutL Proteins
MutS Homolog 2 Protein
Mutation
Neoplasm Proteins
Neoplasms

Source

Open in PubMed

Identifiers

PMID: 9060003
DOI: 10.1016/S1357-4310(96)10055-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9060003-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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