Involvement of genetic polymorphism of alcohol and aldehyde dehydrogenases in individual variation of alcohol metabolism.

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Article

Involvement of genetic polymorphism of alcohol and aldehyde dehydrogenases in individual variation of alcohol metabolism.

Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Nov 1994

Mizoi Y, Yamamoto K, Ueno Y, Fukunaga T, Harada S

Abstract excerpt

The involvement of genetic polymorphism at the alcohol dehydrogenase 2 (ADH2) and aldehyde dehydrogenase 2 (ALDH2) loci in determining blood acetaldehyde levels and the rate of ethanol elimination after ethanol intake was investigated. Sixty-eight healthy subjects ingested 0.4 g of ethanol per kg...

Topics

Acetaldehyde
Adult
Alcohol Dehydrogenase
Aldehyde Dehydrogenase
Chromosome Mapping
Ethanol
Genetic Carrier Screening
Genotype
Homozygote
Humans
Isoenzymes
Japan
Male
Metabolic Clearance Rate
Polymorphism, Genetic
Reference Values

Source

Open in PubMed

Identifiers

PMID: 7695788

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7695788-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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