Article
[Relationship among ALDH2 gene polymorphism, alcohol metabolism and acetaldehyde level in peripheral blood].
Fa yi xue za zhi - 1 Feb 2014
Xiong Hui, Wang Wei, Ye Yi, Yan You-Yi, Xiao Min, Ruan Ruo-Yun, Liao Lin-Chuan
Abstract excerpt
OBJECTIVE: To explore alcohol pharmacokinetics as well as acetaldehyde level in peripheral blood in human subjects with different ALDH2 genotypes after drinking. METHODS: Venous blood samples of 14 unrelated volunteers were collected. Polymerase chain reaction-restriction fragment length polymorphism technology was adopted for DNA extraction and ALDH2 genotyping. The volunteers were asked to drink beer at certain...
Topics
- Alcohol Drinking
- Aldehyde Dehydrogenase
- Aldehyde Dehydrogenase, Mitochondrial
- Ethanol
- Genotype
- Humans
- Polymerase Chain Reaction
- Polymorphism, Genetic
