Article
Ethanol and acetaldehyde metabolism in chinese with different aldehyde dehydrogenase-2 genotypes.
Proceedings of the National Science Council, Republic of China. Part B, Life sciences - 1 Jul 1995
Luu S U, Wang M F, Lin D L, Kao M H, Chen M L, Chiang C H, Pai L, Yin S J
Abstract excerpt
Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) are the major enzymes responsible for ethanol metabolism in humans. Both enzymes exhibit genetic polymorphisms among racial populations. About half of the Chinese population lack mitochondrial ALDH2 activity and such a deficiency has been believed to be a negative risk factor for the development of alcoholism. To assess ethanol and acetaldehyde...
Topics
- Acetaldehyde
- Adolescent
- Adult
- Alcoholism
- Aldehyde Dehydrogenase
- Ethanol
- Genotype
- Heterozygote
- Homozygote
- Humans
- Kinetics
