Article
The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants.
Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism - 1 Jan 2007
Edenberg Howard J
Abstract excerpt
The primary enzymes involved in alcohol metabolism are alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH). Both enzymes occur in several forms that are encoded by different genes; moreover, there are variants (i.e., alleles) of some of these genes that encode enzymes with different characteristics and which have different ethnic distributions. Which ADH or ALDH alleles a person carries influence his or...
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